Direct lineage reprogramming represents a remarkable conversion of cellular and transcriptome states. However, the intermediate stages through which individual cells progress during reprogramming are largely undefined. Here we use single-cell RNA sequencing at multiple time points to dissect direct reprogramming from mouse embryonic fibroblasts to induced neuronal cells. By deconstructing heterogeneity at each time point and ordering cells by transcriptome similarity, we find that...
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Here are the top-rated CEOs according to employee reviews on Glassdoor — 18 from tech make cut
Leaders from technology companies landed in 18 of the 50 spots on Glassdoor’s annual list of the Highest Rated CEOs when the job search website revealed its Employees’ Choice Awards...
Facing new competition from Google, Amazon’s Alexa surpasses 1,000 third-party ‘skills’
That explosion in Alexa “skills” wasn’t our imagination. Amazon’s voice-enabled virtual assistant has reached a milestone of 1,000 third-party skills in less than a year, the company says. Skills are the equivalent of apps, allowing developers to add new capabilities to the Amazon Echo and other devices...
Microsoft Accelerator Demo Day: Cloud and AI innovations from 9 emerging startups
The Summer 2016 cohort of startups at Microsoft Accelerator’s Machine Learning Demo Day in Seattle on Thursday revealed innovations that could save...
From sports news to social media marketing: Ripl raises $1.8M after series of pivots
It took a couple pivots, a lot of grit, and a little bit of sacrifice — but Paul Ingalls...
The 100 best stories from Radium Age sci-fi, which ruled the early 20th century
Solar Impulse plane flies from Ohio to Pennsylvania, sets its sights on New York
One day after a close call, the Solar Impulse 2 round-the-world airplane made a 17-hour trip from Ohio to Pennsylvania...
Guest post: Lessons from the startup that passed on the chance to be the ‘Uber of China’
I’ve always had the entrepreneurial bug in me. In high school, I sold CDs to friends, discounted telescopes from...
Solar Impulse weathers ups and downs, then flies from Ohio to Pennsylvania
The team behind the Solar Impulse 2 airplane’s round-the-world odyssey knows all about reversals of fortune: One day after a disappointing...
Battling digital zombies: Tech security lessons from ‘The Walking Dead’ Season 6
We live in a day and age where new cyber threats emerge daily and staying on top of the latest Information Security (InfoSec) trends can be a challenge. But, exploring and learning doesn’t have to be...