New methods and strategies for the direct functionalization of C–H bonds are beginning to reshape the field of retrosynthetic analysis, affecting the synthesis of natural products, medicines and materials. The oxidation of allylic systems has played a prominent role in this context as possibly the most widely applied C–H functionalization, owing to the utility of enones and allylic alcohols as versatile intermediates, and their...
Tag Archives: Sustainable
Scalable and sustainable electrochemical allylic C–H oxidation
New methods and strategies for the direct functionalization of C–H bonds are beginning to reshape the field of retrosynthetic analysis, affecting the synthesis of natural products, medicines and materials. The oxidation of allylic systems has played a prominent role in this context as possibly the most widely applied C–H functionalization, owing to the utility of enones and allylic alcohols as versatile intermediates, and their...
Sustainable chemistry: Putting carbon dioxide to work
Carbon dioxide is an abundant resource, but difficult for industry to use effectively. A simple reaction might allow it to be used to make commercial products more sustainably than with current processes. See Letter p.215
Nature 531 180 doi: 10.1038/531180a