Tag Archives: reveals

Integrative modelling reveals mechanisms linking productivity and plant species richness

How ecosystem productivity and species richness are interrelated is one of the most debated subjects in the history of ecology. Decades of intensive study have yet to discern the actual mechanisms behind observed global patterns. Here, by integrating the predictions from multiple theories into a single model and using data from 1,126 grassland plots spanning five continents, we detect the clear signals of numerous...

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Super-resolution imaging reveals distinct chromatin folding for different epigenetic states

Metazoan genomes are spatially organized at multiple scales, from packaging of DNA around individual nucleosomes to segregation of whole chromosomes into distinct territories. At the intermediate scale of kilobases to megabases, which encompasses the sizes of genes, gene clusters and regulatory domains, the three-dimensional (3D) organization of DNA is implicated in multiple gene regulatory mechanisms, but understanding this organization remains a challenge. At this...

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The C. elegans adult neuronal IIS/FOXO transcriptome reveals adult phenotype regulators

Insulin/insulin-like growth factor signalling (IIS) is a critical regulator of an organism’s most important biological decisions from growth, development, and metabolism to reproduction and longevity. It primarily does so through the activity of the DAF-16 transcription factor (forkhead box O (FOXO) homologue), whose global targets were identified in Caenorhabditis elegans using whole-worm transcriptional analyses more than a decade ago. IIS and FOXO also regulate important...

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Barcoding reveals complex clonal dynamics of de novo transformed human mammary cells
Most human breast cancers have diversified genomically and biologically by the time they become clinically evident. Early events involved in their genesis and the cellular context in which these events occur have thus been difficult to characterize. Here we present the first formal evidence of the shared and independent ability of basal cells and luminal progenitors, isolated from normal human mammary tissue and...
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Amazon reveals updated delivery drone design in new photos and video
Photos via Amazon.
Amazon today released new photos and a video showing off a redesigned version of its delivery drone. It’s been almost exactly two years since Amazon first announced the “Amazon Prime Air” project and the company today showed off a new prototype drone that will deliver packages through the air directly to customers’ doorsteps in as little as 30 minutes. Here’s...
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