The Flaviviridae are a family of viruses that cause severe human diseases. For example, dengue virus (DENV) is a rapidly emerging pathogen causing an estimated 100 million symptomatic infections annually worldwide. No approved antivirals are available to date and clinical trials with a tetravalent dengue vaccine showed disappointingly low protection rates. Hepatitis C virus (HCV) also remains a major medical problem, with 160 million...
Tag Archives: host
Mark Zuckerberg to host Q&A on Facebook Live — check out some of the early questions
Fresh from hearing what Glenn Beck, Chewbacca Mom and astronauts think about Facebook, CEO Mark Zuckerberg is going to broaden the audience a bit when he conducts a Q&A via...
University of Washington will host first-ever White House workshop on artificial intelligence
Between the University of Washington, a thriving tech community, and strong research institutions,...
Sacramento Kings will host a startup pitch contest during an NBA game
Startup pitch contests happen all over the world at a variety of locations, but an NBA arena usually isn’t the first place you think of as a place where entrepreneurs tout their business ideas.
But the Sacramento Kings are breaking new...
The host galaxy of a fast radio burst
In recent years, millisecond-duration radio signals originating in distant galaxies appear to have been discovered in the so-called fast radio bursts. These signals are dispersed according to a precise physical law and this dispersion is a key observable quantity, which, in tandem with a redshift measurement, can be used for fundamental physical investigations. Every fast radio burst has a dispersion measurement, but none before...
Species difference in ANP32A underlies influenza A virus polymerase host restriction
Influenza pandemics occur unpredictably when zoonotic influenza viruses with novel antigenicity acquire the ability to transmit amongst humans. Host range breaches are limited by incompatibilities between avian virus components and the human host. Barriers include receptor preference, virion stability and poor activity of the avian virus RNA-dependent RNA polymerase in human cells. Mutants of the heterotrimeric viral polymerase components, particularly PB2 protein, are selected...
Virology: Host protein clips bird flu’s wings in mammals
The polymerase enzyme from avian influenza A viruses does not function well in human cells. The protein ANP32A has been identified as the cellular factor mediating a major component of this host restriction. See Letter p.101
Nature 529 30 doi: 10.1038/529030a
All LA schools shut down over message sent from 8chan’s e-mail host, cock.li
(credit: Ken Conley)
The "credible" threat that caused the Los Angeles Unified School District (LAUSD) to close all schools on Tuesday was sent from cock.li, the "meme" e-mail host that also provides e-mail services for 8chan, the 4chan splinter site.
School officials in New York and Los Angeles reportedly both received threats from madbomber@cock.li but only LAUSD took...