Tag Archives: Graded

When graded on tech issues, 2016 presidential candidates don’t do well

(credit: Engine)

On the same day that five key states voted in the presidential primaries, startup lobbying shop Engine took a close look at where the candidates stand on important tech issues like privacy, net neutrality, and patent reform. If your views on those issues align with Engine's, you won't find their 2016 Candidate Report Card an encouraging read.

After taking a...

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Graded Foxo1 activity in Treg cells differentiates tumour immunity from spontaneous autoimmunity

Regulatory T (Treg) cells expressing the transcription factor Foxp3 have a pivotal role in maintaining immunological self-tolerance; yet, excessive Treg cell activities suppress anti-tumour immune responses. Compared to the resting Treg (rTreg) cell phenotype in secondary lymphoid organs, Treg cells in non-lymphoid tissues exhibit an activated Treg (aTreg) cell phenotype. However, the function of aTreg cells and whether their generation can be manipulated are...

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