Tag Archives: division

Analysis: The Division may need “complete rewrite” to fix hacking problems

A video demonstrating how trivial it is to hack the naive online infrastructure of The Division.

Since the release of The Division last month, Ubisoft has been scrambling to stem the widespread use of hacks, cheats, and exploits that have ruined much of the PvP experience in the online-focused multiplayer shooter. But an analysis of client-side cheating programs...

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Metabolic maintenance of cell asymmetry following division in activated T lymphocytes

Asymmetric cell division, the partitioning of cellular components in response to polarizing cues during mitosis, has roles in differentiation and development. It is important for the self-renewal of neuroblasts in Caenorhabditis elegans and fertilized zygotes in Drosophila, and in the development of mammalian nervous and digestive systems. T lymphocytes, upon activation by antigen-presenting cells (APCs), can undergo asymmetric cell division, wherein the daughter cell proximal...

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Cell division: A last-minute decision

Robust quantitative analyses of asymmetric division in certain cells in flies identify the major molecular players and, most interestingly, define a simple equation to explain this complex cellular process. See Letter p.280

Nature 528 196 doi: 10.1038/528196a

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Polarized endosome dynamics by spindle asymmetry during asymmetric cell division

During asymmetric division, fate determinants at the cell cortex segregate unequally into the two daughter cells. It has recently been shown that Sara (Smad anchor for receptor activation) signalling endosomes in the cytoplasm also segregate asymmetrically during asymmetric division. Biased dispatch of Sara endosomes mediates asymmetric Notch/Delta signalling during the asymmetric division of sensory organ precursors in Drosophila. In flies, this has been generalized to...

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