Salesforce today released App Cloud Mobile, a no-cost addition to its software arsenal that the company says integrates previously separate elements for the first time so that both coders and non-techies can create apps...
Tag Archives: development
Co-repressor CBFA2T2 regulates pluripotency and germline development
Developmental specification of germ cells lies at the heart of inheritance, as germ cells contain all of the genetic and epigenetic information transmitted between generations. The critical developmental event distinguishing germline from somatic lineages is the differentiation of primordial germ cells (PGCs), precursors of sex-specific gametes that produce an entire organism upon fertilization. Germ cells toggle between uni- and pluripotent states as they exhibit...
12 things Seattle can teach others about jobs, economic development and building a better city
[Editor’s Note: Tren Griffin, a longtime member of the Seattle region’s technology community, responded earlier this week to New York-based venture capitalist Fred...
GeekWork Picks: Imprintable product supplier SanMar seeks IT Development Manager
Founded in 1971, SanMar Corp. is a national supplier of apparel and accessories for marketing, promotional, and athletic products. The family-owned company is seeking an IT Development Manager to lead the team designing software for SanMar’s Customer Integration, Enterprise Integration Platform...
Development of the gut microbiota and mucosal IgA responses in twins and gnotobiotic mice
Immunoglobulin A (IgA), the major class of antibody secreted by the gut mucosa, is an important contributor to gut barrier function. The repertoire of IgA bound to gut bacteria reflects both T-cell-dependent and -independent pathways, plus glycans present on the antibody’s secretory component. Human gut bacterial taxa targeted by IgA in the setting of barrier dysfunction are capable of producing intestinal pathology when isolated...
The genetic program for cartilage development has deep homology within Bilateria
The evolution of novel cell types led to the emergence of new tissues and organs during the diversification of animals. The origin of the chondrocyte, the cell type that synthesizes cartilage matrix, was central to the evolution of the vertebrate endoskeleton. Cartilage-like tissues also exist outside the vertebrates, although their relationship to vertebrate cartilage is enigmatic. Here we show that protostome and deuterostome cartilage...
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Co-ordinated ocular development from human iPS cells and recovery of corneal function
The eye is a complex organ with highly specialized constituent tissues derived from different primordial cell lineages. The retina, for example, develops from neuroectoderm via the optic vesicle, the corneal epithelium is descended from surface ectoderm, while the iris and collagen-rich stroma of the cornea have a neural crest origin. Recent work with pluripotent stem cells in culture has revealed a previously under-appreciated level...
How Seattle is becoming a worldwide hub for virtual reality technology development
Seattle is already a tech and startup hub. But what is perhaps less known and talked about is how the city is becoming a center for companies and researchers developing virtual reality...
Geek of the Week: Avvo’s Justin Weiss says software development is ‘like getting to solve puzzles for a living’
Avvo software development director Justin Weiss still remembers the days when the legal advice company — where he’s worked for the past eight years — still had that new startup smell. That was back before the company saw its headcount double to...